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Perfusion Systems Perfusion Systems
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Temperature Control Temperature Control
SmartSquirt® Microperfusion
Perfusion Chambers Perfusion Chambers
Rodent Fixation Systems
Brain Slice and Tissue Chambers Brain Slice & Tissue Chambers
Customize a Perfusion System
Complete Electrophysiology Rig
Amplifiers and Stimulators Amplifiers & Stimulators
MDC/Axon Instruments Heka Data Acquisition
Heka Data Acquisition Heka Data Acquisition
Siskiyou Mechanicals Siskiyou Mechanicals
Sutter Manipulators Sutter Manipulators
Micropipette Fabrication Micropipette Fabrication
TMC Air Tables TMC Air Tables
MED64 Multi-Electrode Array Multi-electrode Array
Automated Pipette Patch Clamping Automated Patch Clamping
Port-a-Patch® Planar Patch Clamping
Vesicle Prep Pro Bilayer Apparatus
Filter Wheels Optical Instruments
Functionalized Bio-surfaces Functionalized Bio-surface
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Fixed Platform
Fixed Platform
Basic platform systems are modular, all standard components. Configuration may be changed to suit the user.
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Manual & Motorized Platform
Manual & Motorized Platform
This platform system can be custom tailored to suit the needs of the end user. The platform configuration that is pictured is just one of many that have been produced. They are available in manual or motorized versions.
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Towers
Towers
A versatile platform for mounting a variety of hardware at any level on an isolation table or platform. A complete set of AS series spacers allows flexible vertical adjustment from 2.5- to 12.0-inches in 0.5-inch increments.
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Spacers
Spacers
Platform support rods are a solid solution for supporting platforms or other mechanical hardware. Use these aluminum spacers for spacing of any device that needs to be adjusted in either the vertical or horizontal plane. Spacers can be used by themselves or with ABP series base plates.
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Manual & Motorized Microscope Translator
Manual & Motorized Microscope Translator
Our crossed roller translators are available in motorized and manual versions. Motorized versions can be controlled with any e series and MC2000 controllers. Our controllers drive the stage through a closed loop interface between the controller and the motor encoder.
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Economy Manual Translator
Economy Manual Translator
Our economy microscope translators are designed to be stable XY translators for fixed stages experiments. MXMS-100 series translators have a full 25 mm of XY translation and use ball transfer pads in the back two bearing locations. These ball transfer pads have proven themselves as a solid alternative to full crossed roller translators.
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SD-10 Mini Manual Manipulator
SD-10 Mini Manual ManipulatorBrownlee Amplifiers
The SD-10 is a miniature micromanipulator that is ideal for positioning applications that require micron-level resolution. They use a precision rolled 80TPI lead screw for smooth positioning along their entire travel. The miniature dovetail slide uses an adjustable spring loaded gib design to ensure stability, straightness of travel and also works as a locking mechanism. The fourth axis can be set thru 360° of motion.
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MX-110 Manual Post Mount Manipulator
MX-110 Manual Post Mount Manipulator
Perfect for mounting next to high microscope stages without using towers or platforms, the MX-110 post-mount manipulator comes pre-mounted to a 12.36 inch high rod and base. This drift-free manual manipulator includes a tilting axial approach on the 4th axis with 22 mm of travel, and can be rotated away for easy probe replacement.
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SD-130 Compact Manual Manipulator
SD-130 Compact Manual ManipulatorBrownlee Amplifiers
The SD-130 Manipulator is designed to maximize available space. The narrow profile design allows multiple manipulators to be placed in one quadrant. The SD-130 provides 38mm coarse and 5mm fine positioning travel in the X axis. Two and a half turns of the coarse adjustment knob will fully retract the device in the X axis. It is equipped with a probe clamp for easy change of implement.
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SD-160 Full Manual Manipulator
SD-160 Full Manual Manipulator
Unlike manipulators with rack and pinion drive, the SD-160 uses a spring loaded lead screw design against a solid stop, which ensures drift-free operation. The SD-160 incorporates fast-pitch, screw drive positioning, and smooth ball bearing motion in the X, Y, Z, and Q axes for precision positioning. The top stage tilts 360° and includes 22mm of travel along the probe axis -- ideal for axial cell probing.
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Motorized Manipulators
Motorized Manipulators
The MX7600 motorized crossed roller bearing micromanipulator is ideal for patch recording experiments. The MX7600 offers exceptionally smooth linear travel and uses a precision preloaded lead screw to ensure drift-free operation.
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Controller Dial
Controller Dial
The MC1000e-R 4-axis dial controller acts as a remote micrometer control for actuators, manipulators, and stages. It uses encoder feedback from our closed loop devices to create an electronic link between the controller dial and the device being driven. This direct coupling to the encoder ensures smooth and coordinated motion between the controller and the drive.
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Controller Joystick
Controller Joystick
The joystick controller is designed for coarse micron level positioning of actuators, manipulators, and stages. The joystick control is proportional from slow to high through the travel range of the joystick motion.
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Controller Push-Button
Controller Push-Button
The MC1000e is a simple push-button controller with submicron positioning capability that is compatible with our 800 and 7000 series actuators, manipulators, and stages.
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Controller Push-Button & Target
Controller Push-Button & Target
A simple push-button controller with submicron positioning capability and a user selected target feature. The TARGET/RETRACT feature allows the user to set a target location at a desired point.
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Controller Junction Switch Box
Controller Junction Switch Box
The ABDC switching box allows control of one to four 4-axis micromanipulators by one controller. The basis of the design is simple and requires only an extra controller junction box for each added micromanipulator or motor drive group (up to four per group).
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Hydraulic Manipulators
Hydraulic Manipulatorsmanip-mm1-mm3.html
Smooth motion and instant response to hand adjustments makes the MX6600 ideal for long term intracellular recordings. The water based hydraulic mechanism has a thermal expansion two to three times less than that of oil based systems, thus minimizing drift to less than 2 μm per hour at constant temperatures.
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Hydraulic Manipulators
Piezo Switchermanip-mm1-mm3.html
The piezo solution switcher uses a high-speed piezo flexure guided nanopositioner to move pipette tips in solution switching applications. It can move an electrode tip across a 5 µm thick theta glass septum. This system is ideal for measuring cellular response to drugs or other elements in solution.
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Headstage Holders
Headstage & Pipette Holders
The MXC-45D’s unique design allows repeatable electrode replacement with a simple but accurate rotating clamp. The rotating portion is configured such that the probe /pipette rotates up and away from the experiment at a 45° angle through a full 180°. The repeatable stop returns to its location with micron level accuracy and the stop’s orientation can be changed simply by loosening a single 1⁄4-20 cap screw.
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Pipette Holders
Headstage & Pipette Holders
MXE & MXP series pipette holders utilize ceramic rods to eliminate drift introduced by plastic mounting rods. Features include: solid ceramic mounting rod, compatible with most amplifiers, and eliminated drift. Pipette holders come in a variety of lengths to accommodate a wide range of setups.
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Chamber Shuttle
Chamber Shuttle
Three axis Chamber Shuttle System. One inch working travel in XYZ. Magnetic coupling allows quick withdrawal of perfusion chamber from working area.
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Chamber
Siskiyou Perfusion Chamber
Perfusion chambers have embedded magnets that are conveniently located to retain perfusion plumbing and ground plugs. A standard 22 mm cover slip is used to create the chamber bottom that is attached with vacuum grease, silicon, or parafilm. There are two plastic retention screws for added security.
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Electrode Holders
Electrode Holders
Stable-tip electrode holders eliminate the final instability link in the electrophysiology experimental setup. It features a thermally stable base material which is coated with aluminaoxide. This coating has two benefits: first, it is non-conductive so the holder does not act as an electrical antenna; second, it is very resistant to corrosion.
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Pipette Pullers
Pipette Pullers
The dual stage pipette puller uses several unique methods to make consistent electrodes pull after pull. The theory of operation is based on time management and millivolt control of the element for both first and second pulls. By controlling the time, or at least establishing a time basis, the user can create a pipette shape and length consistently and repeatedly.
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Tissue Slicer
Tissue Slicer
The tissue slicer consistently slices sectioned cortical or hippocampal tissue to either a 200-, 300-, or 400-μm thickness in a straightforward operation. Thicknesses are selected by simply replacing the lead screw on the frame winder. This style of tissue slicer ensures consecutive slices of the specifically sectioned area.
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Opto Positioner
Opto Positioner
The IS-OGP provides a simple, complete solution that adds a laser light source to your microscope for optogenetics research. It positions a small (10um typical with 20X objective) stimulation spot to any location within the field of view.
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